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Safety and immunogenicity of a live attenuated influenza H5 candidate vaccine strain A/17/turkey/Turkey/05/133 H5N2 and its priming effects for potential pre-pandemic use: a randomised, double-blind, placebo-controlled trial

Pitisuttithum P.

Дата публикации: 2021-04-27

Дата публикации в реестре: 2021-10-05T18:23:10Z

Аннотация:
Ключевые слова:
avian influenza vaccine, immunoglobulin A, immunoglobulin G, inactivated virus vaccine, live vaccine, neutralizing antibody, orniflu, oseltamivir, placebo, influenza vaccine, live vaccine, neutralizing antibody, placebo, virus antibody, adult, antibody response, antibody titer, arm movement limitation, arm weakness, Article, burning sensation, chill, clinical evaluation, controlled study, coughing, diarrhea, double blind procedure, drug effect, drug safety, drug tolerability, dyspnea, fatigue, female, follow up, headache, helper cell, hemagglutination inhibition, human, immune response, immunization, immunoassay, immunogenicity, Influenza A virus (H5N1), Influenza A virus (H5N2), Influenza A virus /17/turkey/Turkey/05/133 H5N2, injection site pain, major clinical study, male, microneutralisation assay, myalgia, nausea, nose obstruction, outcome assessment, pandemic, plasmablast, postnasal drip, priority journal, randomized controlled trial, rash, red nose, rhinorrhea, seroconversion, sore throat, taste disorder, Thailand, urticaria, virus shedding, virus strain, adolescent, animal, blood, Drug-Related Side Effects and Adverse Reactions, hemagglutination inhibition test, immunology, Influenza A virus (H5N2), Influenza, Human, intramuscular drug administration, intranasal drug administration, middle aged, normal human, pathology, plasma cell, serodiagnosis, T lymphocyte, young adult, Administration, Intranasal, Adolescent, Adult, Animals, Antibodies, Neutralizing, Antibodies, Viral, Double-Blind Method, Drug-Related Side Effects and Adverse Reactions, Female, Healthy Volunteers, Hemagglutination Inhibition Tests, Humans, Influenza A Virus, H5N1 Subtype, Influenza A Virus, H5N2 Subtype, Influenza Vaccines, Influenza, Human, Injections, Intramuscular, Male, Middle Aged, Neutralization Tests, Placebos, Plasma Cells, T-Lymphocytes, Thailand, Vaccines, Attenuated, Young Adult

Тип: info:eu-repo/semantics/journal-article

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