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Non-immunogenic recombinant staphylokinase versus alteplase for patients with acute ischaemic stroke 4·5 h after symptom onset in Russia (FRIDA): a randomised, open label, multicentre, parallel-group, non-inferiority trial

Gusev E.I., Martynov M.Y., Nikonov A.A., Shamalov N.A., Semenov M.P., Gerasimets E.A., Yarovaya E.B., Semenov A.M., Archakov A.I., Markin S.S., Aksentiev S.B., Yunevich D.S., Alasheev A.M., Androfagina O.V., Bobkov V.V., Choroshavina K.V., Chefranova J.Y., Lykov Y.A., Chuprina S.E., Vorobev A.A., Dobrovolskiy A.V., Elemanov U.A., Fedaynin S.A., Gorbachev V.I., Korobeinikov I.V., Greshnova I.V., Korsunskaya L.L., Nikonova A.A., Kudinov V.A., Artyushev R.I., Kutsenko V.A., Nesterova V.N., Nizov A.A., Girivenko A.I., Orlovsky A.A., Ponomarev E.A., Popov D.V., Pribylov S.A., Semikhin A.S., Timchenko L.V., Jadan O.N., Zakharov S.A., Chirkov A.N., Zhukovskaya N.V., The FRIDA Study Group

Дата публикации в реестре: 2022-10-06T17:11:53Z

Аннотация:
Ключевые слова:
auR protein, Staphylococcus aureus, fibrinolytic agent, metalloproteinase, recombinant protein, tissue plasminogen activator, aged, brain ischemia, clinical trial, comparative study, controlled study, double blind procedure, female, human, immunology, male, middle aged, multicenter study, randomized controlled trial, Russian Federation, time to treatment, very elderly, Aged, Aged, 80 and over, Double-Blind Method, Female, Fibrinolytic Agents, Humans, Ischemic Stroke, Male, Metalloendopeptidases, Middle Aged, Outcome Assessment, Health Care, Recombinant Proteins, Russia, Time-to-Treatment, Tissue Plasminogen Activator

Тип: Article

Права: open access

Источник: The Lancet Neurology

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