Molecular cytogenetic and cytopostgenomic analysis of the human genome of the human
genome to uncover mechanisms of genetic (brain/neurodevelopmental) diseases
Chromosome instability, aging and brain diseasesChromosome
instability (CIN) has been repeatedly associated with aging and progeroid phenotypes
Somatic mosaicism in the diseased brainIt is hard to believe that all the cells of a human brain share identical
genomes. Indeed, single
Environmental epigenetics and genome flexibility: Focus on 5-hydroxymethylcytosine modifications for mammalian
genome regulation and its flexibility. DNA methylation and demethylation is a key
Follow-up studies on genome damage in children after Chernobyl nuclear power plant accident, and micronuclei. The presence of rogue cells confirmed internal contamination.
Genome instability Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform to clone and manipulate in Escherichia coli owing to the size and occasional
instability of the
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