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Intramolecular alkene Friedel-Crafts cyclization of 1-allyl-1-N-(ortho- alkylphenylamino)cyclohexanes. A useful route to alkyl substituted dihydrospiro[(1H)quinoline-2,1′-cyclohexanes]. Unprecedented ipso-substitution of alkyl groupsAn unprecedented intramolecular Friedel-Crafts ipso-alkylation at the ortho-alkyl group of the N

A simple approach for the synthesis of azocine alkaloids: The total synthesis of megallanesine and intramolecular Friedel-Craft reaction of an ester is presented. This method allows synthesis of azocine ring

New synthetic approach to substituted isoindolo[2,1-a]quinoline carboxylic acids via intramolecular Diels-Alder reaction of 4-(N-furyl-2)-4- arylaminobutenes-1 with maleic anhydride intramolecular [4+2] exo-cycloaddition reaction. Treatment of the tricyclic compounds with phosphoric acid

Experimental evidence for intramolecular ipso substitution of alkyl groupsAn acid-mediated intramolecular Friedel-Crafts intramolecular alkene alkylation of the ortho

Synthesis, In Silico and In Vivo Toxicity Assessment of Functionalized Pyridophenanthridinones via Sequential MW-Assisted Intramolecular Friedel-Crafts Alkylation and Direct C–H Arylation, these N-aryl-N-(2-bromobenzyl) cinnamamides 8a–f were subjected to a TFA-mediated intramolecular Friedel-Crafts

CuBr2-catalyzed alkylation of furans with benzyl alcohols and benzaldehydes. Domino reactions including this alkylation as a key step is reported. Reaction proceeds efficiently under mild reaction conditions requiring no inert atmosphere

Stability and activity of Zn/MCM-41 materials in toluene alkylation: Microwave irradiation vs continuous flow nitrate as precursor and tested for activity and stability in the Friedel-Crafts alkylation of toluene

Synthesis and transformations of 6-acetyl-1,2,3,4-tetrahydro-2,2,4,7-tetramethylquinolineBy acylation of 1,2,3,4-tetrahydro-2,2,4,7-tetramethylquinoline under the conditions of the Friedel–Crafts

Evaluation of acid properties of mechanochemically synthesized supported niobium oxide catalysts in the alkylation of toluene mechanochemically synthesized as catalysts for Friedel-Crafts alkylation reactions. The physicochemical properties

An efficient synthesis of isoindolo[2,1-a]quinoline derivatives via imino Diels-Alder and intramolecular Diels-Alder reactions with furan,2,3,4-tetrahydroquinolines bearing a furan fragment via the intramolecular Diels-Alder reaction is reported. The synthesis

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