Chaperone Sigma1R mediates the neuroprotective action of afobazole in the 6-OHDA model of Parkinson’s disease that the ligand
activation of the sigma-1 chaperone (Sigma1R) promotes
neuroprotection. The multitarget drug
New Insights into the Roles of Metalloproteinases in Neurodegeneration and Neuroprotection peptide by metallopeptidases can also be both intra- and extracellular depending on the
activity Mechanism of neuroprotective effect of mGluR4 agonists. It is suggested that the
activation of mGluR4 may have a
neuroprotective effect. Role of excitotoxicity