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Unveiling the methionine cycle: a key metabolic signature and NR4A2 as a methionine-responsive oncogene in esophageal squamous cell carcinoma

Jin X., Liu L., Liu D., Wu J., Wang C., Wang S., Wang F., Yu G., Jin X., Xue Y.-W., Jiang D., Ni Y., Yang X., Wang M.-S., Wang Z.-W., Orlov Y.L., Jia W., Melino G., Liu J.-B., Chen W.-L.

Дата публикации в реестре: 2025-05-27T14:19:26Z

Аннотация:
Ключевые слова:
Animals, Cell Line, Tumor, Cell Proliferation, Esophageal Neoplasms, Esophageal Squamous Cell Carcinoma, Gene Expression Regulation, Neoplastic, Humans, Methionine, Mice, Mice, Nude, Nuclear Receptor Subfamily 4, Group A, Member 2, Oncogenes, ademetionine, celecoxib, messenger RNA, methionine, nuclear receptor related factor 1, somatomedin B, nuclear receptor related factor 1, animal experiment, animal model, Article, cancer growth, cancer survival, cell proliferation, clinical article, cohort analysis, controlled study, esophageal squamous cell carcinoma, esophageal squamous cell carcinoma cell line, gene expression, human, human cell, human tissue, metabolic parameters, mouse, multiomics, nonhuman, NR4A2 gene, oncogene, pathogenesis, RNA methylation, transcription initiation, animal, drug effect, esophageal squamous cell carcinoma, esophagus tumor, gene expression regulation, genetics, metabolism, nude mouse, oncogene, pathology, tumor cell line

Тип: Article

Источник: Cell death and differentiation

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