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Effect of early sleep apnoea treatment with adaptive servo-ventilation in acute stroke patients on cerebral lesion evolution and neurological outcomes: study protocol for a multicentre, randomized controlled, rater-blinded, clinical trial (eSATIS: early Sleep Apnoea Treatment in Stroke).MethodseSATIS is an open-label, multicentre (6 centres in 4 countries), interventional, randomized controlled trial

A Systematic Review and International Web-Based Survey of Randomized Controlled Trials in the Perioperative and Critical Care Setting: Interventions Increasing Mortality by randomized trials to increase mortality in these clinical settings. Design: A systematic review

Influence of 5-hydroxymethyluracil on the dynamics of angiogenic growth factors in the perioperative period of surgical myocardial revascularization: results of a randomized trial in the perioperative period of surgical myocardial revascularization: results of a randomized trial

Treatment of climacteric symptoms with an ammonium succinate-based dietary supplement: a randomized, double-blind, placebo-controlled trial the course of a 3-month, randomized, double-blind, placebo-controlled study. General clinical assessment

Two live attenuated vaccines against recent low–and highly pathogenic H7N9 influenza viruses are safe and immunogenic in ferrets and immunogenicity in the ferret model in order to choose the most promising one for a phase I clinical trial. The A

Non-immunogenic recombinant staphylokinase versus alteplase for patients with acute ischaemic stroke 4.5 h after symptom onset in Russia (FRIDA): a randomised, open label, multicentre, parallel-group, non-inferiority trial, to March 23, 2019, 336 (87%) were included in the trial. 168 (50%) patients were randomly assigned

Cost-effectiveness of a screening strategy for Q fever among pregnant women in risk areas: a clustered randomized controlled trial trial in which primary care midwife centres in Q fever risk areas are randomized to recruit pregnant

Continuous infusion versus intermittent administration of meropenem in critically ill patients (MERCY): A multicenter randomized double-blind trial. Rationale and design dummy, multicenter randomized controlled trial (1:1 allocation ratio). Setting: Tertiary and University

Clinical and pharmacological comparison of current antifibrotic drugs for therapy of idiopathic pulmonary fibrosis. Results of completed randomized phase III clinical trials (RCT) showed the ability of these drugs

The Prospects of tumor necrosis factor α inhibitors use in patients with COVID-19 in Russia, which are at different stages of clinical trials. We conclude that randomized clinical trials

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