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Five distinct reassortants of H5N6 highly pathogenic avian influenza A viruses affected Japan during the winter of 2016–2017 genetic reassortant among Chinese clade 2.3.4.4 H5N6 HPAIVs. In addition, 2 NS clusters and a PA cluster
Application of real time RT-PCR for the genetic homogeneity and stability tests of the seed candidates for live attenuated influenza vaccine production priority because of safety concerns. Live attenuated influenza vaccine (LAIV) viruses are 6:2 reassortants
Implementation of new approaches for generating conventional reassortants for live attenuated influenza vaccine based on Russian master donor viruses (LAIV). The classical strategy for generating LAIV reassortants is robust, but has some disadvantages
Orthohantaviruses, emerging zoonotic pathogens for the high genome diversity are mainly caused by point mutations and reassortment, which occur in the genome
Novel reassortant of H1N1 swine influenza virus detected in pig population in Russia as “mixing vessels” for reassortment. Two influenza A/H1N1 virus strains, A/swine/Siberia/1sw/2016 and A
Engineering by reverse genetics and characterization of the new re-assortant influenza virus strain H5N1Reverse genetics was applied to engineering of the reassortant vaccine candidate strain against
Does pandemic A/H1N1 virus have the potential to become more pathogenic? virus include a stable virulence phenotype and a lack of propensity to reassort with seasonal strains
Characterization of reverse genetics-derived cold-adapted master donor virus a/Leningrad/134/17/57 (H2N2) and reassortants with H5N1 surface genes in a mouse model (MDV), we produced and characterized three rg H5N1 reassortant viruses carrying modified HA and intact
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