Macrophage-specific expression of IL-37 in hyperlipidemic mice attenuates atherosclerosis in decreased mRNA (
e.g., IL-1B, IL-6, and IL-12) and secreted protein production (
e.g., IL-6, M-CSF, and ICAM-1
Macrophage-specific expression of IL-37 in hyperlipidemic mice attenuates atherosclerosis in decreased mRNA (
e.g., IL-1B, IL-6, and IL-12) and secreted protein production (
e.g., IL-6, M-CSF, and ICAM-1
Hyperlipidemia-induced cholesterol crystal production by endothelial cells promotes atherogenesis to target inflamed endothelium, shows reduced atherosclerosis and CC formation in Apo
E -/- mice. Our