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Multiple Sites of the Cleavage of 21- and 25-Mer Encephalytogenic Oligopeptides Corresponding to Human Myelin Basic Protein (MBP) by Specific Anti-MBP Antibodies from Patients with Systemic Lupus Erythematosus-Sepharose in contrast to canonical proteases hydrolyze effectively only myelin basic protein (MBP), but not many other
Candidate SNP markers of aggressiveness-related complications and comorbidities of genetic diseases are predicted by a significant change in the affinity of TATA-binding protein for human gene promoters heuristic keywords. Near the known binding sites for TATA-binding protein (TBP) in human gene promoters, we
Integrative analysis of miRNA and mRNA sequencing data reveals potential regulatory mechanisms of ACE2 and TMPRSS2retinoblastoma binding protein
Volume of Hsp90 Protein-Ligand Binding Determined by Fluorescent Pressure Shift Assay, Densitometry, and NMR for the investigated protein-ligand systems. Protein-ligand binding volumes were negative, suggesting that the protein
Alterations in hemagglutinin receptor-binding specificity accompany the emergence of highly pathogenic avian influenza viruses this hypothesis, we compared a number of LPAIVs and HPAIVs for their HA-mediated binding and NA
New targets for HIV drug discovery to develop drug resistance to. In addition, there are virus-related targets (capsid and RNAse H) that have
Inhibition of the eukaryotic 80S ribosome as a potential anticancer therapy: A structural perspectiveProtein biosynthesis is a vital process for all kingdoms of life. The ribosome is the massive
Hybrid inorganic-organic capsules for eficient intracellular delivery of novel siRNAs against influenza A (H1N1) virus infectionRNA binding protein
Artificial anti-HIV-1 immunogen comprising epitopes of broadly neutralizing antibodies 2f5, 10e8, and a peptide mimic of VRC01 discontinuous epitopeThe construction of artificial proteins using conservative B-cell and T-cell epitopes is believed
Structure-based drug repurposing for targeting Nsp9 replicase and spike proteins of severe acute respiratory syndrome coronavirus 2 and evaluation are warranted to establish how these drug compounds target the Nsp9 replicase and spike proteins
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