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Development and approval of live attenuated influenza vaccines based on Russian master donor viruses: Process challenges and success storiesclinical trial (topic)

Randomized crossover comparative study of safety, tolerance and pharmacokinetics of primapur vs. gonal-f upon single-dose subcutaneous administration in healthy volunteersThe purpose of the current phase I study was to establish bioequivalence, safety, and tolerance

Effects of testosterone supplementation on markers of the metabolic syndrome and inflammation in hypogonadal men with the metabolic syndrome: The double-blinded placebo-controlled Moscow study- A randomized, placebo-controlled, double-blinded, phase III trial of 184 men suffering from both

Safety and efficacy of an rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine: an interim analysis of a randomised controlled phase 3 trial in Russia in phase 1/2 clinical trials. Here, we report preliminary results on the efficacy and safety of Gam

The Effect of Preexisting Immunity on Virus Detection and Immune Responses in a Phase II, Randomized Trial of a Russian-Backbone, Live, Attenuated Influenza Vaccine in Bangladeshi ChildrenBackground: In a 2012 Phase II clinical trial, 300 Bangladeshi children aged 24 to 59 months

The role of reference intervals of laboratory tests in early phase clinical research in healthy volunteers from positions of foreign and national guidelines of early phase clinical research and with regard

Renal effects of ularitide in patients with decompensated heart failure urodilatin in DHF patients. Methods: In SIRIUS II, a double-blind phase II trial, 221 patients hospitalized

Atezolizumab and Bevacizumab in Therapy for Patients with Hepatocellular Carcinoma in Real Clinical Practice
Atezolizumab and Bevacizumab in Therapy for Patients with Hepatocellular Carcinoma in Real Clinical

H7N9 live attenuated influenza vaccine in healthy adults: A randomised, double-blind, placebo-controlled, phase 1 trial volunteers. Methods: We did a phase 1, double-blind, randomised, placebo-controlled trial in Saint Petersburg

Safety and immunogenicity of trivalent inactivated influenza vaccine in adults 60 years of age and older: a phase II, a randomized, comparative trial in Kazakhstan versus commercial vaccine VAXIGRIP® for immunogenicity and safety in the course of clinical trial phase

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