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Pyrrolo[3,2-c]pyridine derivatives as inhibitors of platelet aggregationA series of pyrrolo[3,2-c]pyridines, isosteres of the antithrombotic drug ticlopidine, has been

Recyclization of benzofuropyridines by the action of activated alkynes in the synthesis of spiro[benzofuropyridines], representatives of a new class of acetylcholinesterase inhibitorsA study was carried out on the domino transformations of tetrahydrobenzofuro[2,3-c

Pyrrolo[2,1-a]isoquinoline scaffold in drug discovery: Advances in synthesis and medicinal chemistry

Synthesis of Novel Benzo[b][1,6]naphthyridine Derivatives and Investigation of Their Potential as Scaffolds of MAO Inhibitors for the first time. Among the newly synthesized derivatives, 5c–h proved to be MAO B inhibitors with potency

Reductive domino reaction to access chromeno[2,3-c]isoquinoline-5-amines with antiproliferative activities against human tumor cells and results in the formation of nineteen 12H-chromeno[2,3-c]isoquinoline-5-amine derivatives. Four new bonds

3-benzazecine-based cyclic allene derivatives as highly potent P-glycoprotein inhibitors overcoming doxorubicin multidrug resistanceAim: Enamino 3-benzazecine compounds, incorporating the C6-C8 allene system, were synthesized

Synthesis of Isomeric 3-Benzazecines Decorated with Endocyclic Allene Moiety and Exocyclic Conjugated Double Bond and Evaluation of Their Anticholinesterase Activity-benzazecines incorporating an endocyclic C6–C8 allene fragment and the -ylidene derivatives 6-methoxymethylene

Tandem cleavage of hydrogenated beta- and gamma-carbolines - New practical synthesis of tetrahydroazocino[4,5-b]indoles and tetrahydroazocino[5,4-b]-indoles showing acetylcholinesterase inhibitory activity50 values in the micromolar range, compound 17 being the most potent (IC50 = 8.7 mum). ((C) Wiley

Advances in synthesis of novel annulated azecines and their unique pharmacological propertiesAnnulated azecines, mostly partially saturated benzo[d]azecine and dibenzo[c,g]azecine fusion

Ester derivatives of annulated tetrahydroazocines: A new class of selective acetylcholinesterase inhibitors

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