Поиск

Материалов:
1 005 012

Репозиториев:
30

Авторов:
596 024

Автор

Ключевое слово

Тип статьи

DOI

ORCID

Дополнительно:

Период публикации

Репозиторий

По вашему запросу найдено документов: 1005012

Страница 1 из 100502

In-vitro and in-silico studies of annelated 1,4,7,8-tetrahydroazocine ester derivatives as nanomolar selective inhibitors of human butyrylcholinesterase

Modesto De Candia, Titov Alexander A., Viayna Antonio, Kulikova Larisa N., Purgatorio Rosa, Piergiovanni Brigida, Niso Mauro, Catto Marco, Voskressensky Leonid G., Luque F.Javier, Altomare Cosimo D.

Recyclization of benzofuropyridines by the action of activated alkynes in the synthesis of spiro[benzofuropyridines], representatives of a new class of acetylcholinesterase inhibitors

Voskressensky L.G., Kovaleva S.A., Borisova T.N., Eresko A.B., Tolkunov V.S., Tolkunov S.V., Listratova A.V., Altomare C., Varlamov A.V., De Candia M.

Synthesis of Isomeric 3-Benzazecines Decorated with Endocyclic Allene Moiety and Exocyclic Conjugated Double Bond and Evaluation of Their Anticholinesterase Activity

Titov A.A., Purgatorio R., Obydennik A.Y., Listratova A.V., Borisova T.N., De Candia M., Catto M., Altomare C.D., Varlamov A.V., Voskressensky L.G.

competitive AChE inhibitor with a low micromolar inhibition constant value (Ki = 4.9 μM), equipotent

Ester derivatives of annulated tetrahydroazocines: A new class of selective acetylcholinesterase inhibitors

Carotti A., Catto M., Borisova T.N., Varlamov A.V., Méndez-Álvarez E., Soto-Otero R., Voskressensky L.G., Altomare C., De Candia M.

acted as AChE inhibitors in vitro, with IC50 values ranging from 5 to 40 μM. The most potent compounds

Advances in synthesis of novel annulated azecines and their unique pharmacological properties

Listratova A.V., Samarelli F., Titov A.A., Purgatorio R., De Candia M., Catto M., Varlamov A.V., Voskressensky L.G., Altomare C.D.

Investigating 1,2,3,4,5,6-hexahydroazepino[4,3-b]indole as scaffold of butyrylcholinesterase-selective inhibitors with additional neuroprotective activities for Alzheimer's disease

Purgatorio R., Catto M., Carrieri A., Pisani L., Toma M., Ivanova O.A., Voskressensky L.G., Altomare C.D., De Candia M., De Palma A.

behaves as a mixed-type inhibitor, resulted the most potent (IC50 0.17 μM)and selective (>100-fold

Physicochemical properties and antimicrobial activity of new spirocyclic thieno[2,3-d]pyrimidin-4(3H)-one derivatives

Altamura C., Denora N., Cellamare S., Nuzzolese M., Voskressensky L.G., Varlamov A.V., Altomare C.D., De Candia M., De Vito D.

and fungi at the maximum test concentration (500 μM). Implications of the physicochemical properties

Scouting around 1,2,3,4-Tetrahydrochromeno[3,2-c]pyridin-10-ones for Single- and Multitarget Ligands Directed towards Relevant Alzheimer's Targets

Purgatorio R., Kulikova L.N., Pisani L., Catto M., Carrieri A., Cellamare S., Beloglazkin A.A., Voskressensky L.G., Altomare C.D., De Candia M., De Palma A., Reza Raesi G.

activities. Moreover, compound 1 f, a potent and selective human MAO B inhibitor (IC50=0.89 μM), proved

Evaluation of Water-Soluble Mannich Base Prodrugs of 2,3,4,5-Tetrahydroazepino[4,3-b]indol-1(6H)-one as Multitarget-Directed Agents for Alzheimer's Disease

Purgatorio R., Catto M., Rullo M., Pisani L., Denora N., Carrieri A., Nevskaya A.A., Voskressensky L.G., Altomare C.D., De Candia M.

butyrylcholinesterase inhibitor (hBChE, IC5013 nM) and protective agent in NMDA-induced neurotoxicity, in in vivo assays

Nature-Inspired 1-Phenylpyrrolo[2,1-a]isoquinoline Scaffold for Novel Antiproliferative Agents Circumventing P-Glycoprotein-Dependent Multidrug Resistance

Nevskaya A.A., Purgatorio R., Borisova T.N., Varlamov A.V., Anikina L.V., Obydennik A.Y., Nevskaya E.Y., Niso M., Colabufo N.A., Carrieri A., Catto M., De Candia M., Voskressensky L.G., Altomare C.D.

tumor cell lines in the low micromolar range (IC50 < 20 μM) and to inhibit in vitro the efflux pumps P

Страница 1 из 100502