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Physiologically based pharmacokinetic model for predicting the biodistribution of albumin nanoparticles after induction and recovery from acute lung injury
Kutumova Elena O., Akberdin Ilya R., Egorova Vera S., Kolesova Ekaterina P., Parodi Alessandro, Pokrovsky Vadim S., Zamyatnin, Jr Andrey A., Kolpakov Fedor A.
Atomic Force Microscopy: A Versatile Tool in Cancer Research
Persano F., Parodi A., Pallaeva T., Kolesova E., Zamyatnin A.A.Jr., Pokrovsky V.S., De Matteis V., Leporatti S., Cascione M.
the quantification of parameters that were previously disregarded only a few decades ago. A notable example
Lysine oxidase exposes a dependency on the thioredoxin antioxidant pathway in triple-negative breast cancer cells
Chepikova O.E., Malin D., Strekalova E., Lukasheva E.V., Cryns V.L., Zamyatnin A.A.Jr.
to fundamental differences between LO and lysine depletion. LO rapidly induces ROS with a return to baseline
Synthesis, Characterization, and Preclinical Evaluation of a Small-Molecule Prostate-Specific Membrane Antigen-Targeted Monomethyl Auristatin e Conjugate
Machulkin A.E., Uspenskaya A.A., Zyk N.U., Nimenko E.A., Ber A.P., Petrov S.A., Polshakov V.I., Shafikov R.R., Skvortsov D.A., Plotnikova E.A., Pankratov A.A., Smirnova G.B., Borisova Y.A., Pokrovsky V.S., Kolmogorov V.S., Vaneev A.N., Khudyakov A.D., Chepikova O.E., Kovalev S., Erofeev A., Gorelkin P., Beloglazkina E.K., Zyk N.V., Khazanova E.S., Majouga A.G., Zamyatnin Jr A.A.
is chemotherapy, which has a wide range of side effects. One of the solutions to this challenge is targeted
In Silico, In Vitro, and Clinical Investigations of Cathepsin B and Stefin A mRNA Expression and a Correlation Analysis in Kidney Cancer
Rudzinska-Radecka M., Frolova A.S., Balakireva A.V., Gorokhovets N.V., Pokrovsky V.S., Sokolova D.V., Korolev D.O., Potoldykova N.V., Vinarov A.Z., Parodi A., Zamyatnin A.A.Jr.
The cysteine protease Cathepsin B (CtsB) plays a critical role in multiple signaling pathways
Biologics-based technologies for highly efficient and targeted RNA delivery
Kostyusheva A., Brezgin S., Ponomareva N., Frolova A., Lunin A., Bayurova E., Tikhonov A., Slatinskaya O., Demina P., Kachanov A., Babayeva G., Khan I., Khochenkov D., Khochenkova Y., Sokolova D., Silachev D., Maksimov G., Khaydukov E., Pokrovsky V.S., Zamyatnin A.A.Jr., Parodi A., Gordeychuk I., Chulanov V., Kostyushev D.
efficiency of this system in vitro and in vivo. These technologies can be adapted for manufacturing a wide
Comparative lipidomic analysis of inflammatory mediators in the aqueous humor and tear fluid of humans and rabbits
Chistyakov D.V., Azbukina N.V., Astakhova A.A., Goriainov S.V., Chistyakov V.V., Tiulina V.V., Baksheeva V.E., Kotelin V.I., Fedoseeva E.V., Philippov P.P., Kiseleva O.A., Bessmertny A.M., Senin I.I., Iomdina E.N., Sergeeva M.G., Zernii E.Y., Zamyatnin A.A.Jr.
Introduction: Ocular inflammation is a key pathogenic factor in most blindness-causing visual
Alterations in Tear Content of Inflammatory Oxylipines Associated with Perioperative Dry Eye Syndrome
Chistyakov D.V., Azbukina N.V., Astakhova A.A., Goriainov S.V., Chistyakov V.V., Tiulina V.V., Gancharova O.S., Baksheeva V.E., Philippov P.P., Sergeeva M.G., Senin I.I., Zernii E.Y., Zamyatnin A.A.Jr.
OME) under oxidative conditions indicates a significant contribution of oxidative stress to the development
Amino acid degrading enzymes and their application in cancer therapy
Pokrovsky V.S., Chepikova O.E., Davydov D.Z., Lukashev A.N., Lukasheva E.V., Zamyatnin A.A.Jr.
was to summarize recent progress in the relationship between amino acids metabolism and cancer therapy, with a
Inflammation in dry eye syndrome: Identification and targeting of oxylipin-mediated mechanisms
Chistyakov D.V., Gancharova O.S., Baksheeva V.E., Tiulina V.V., Goriainov S.V., Azbukina N.V., Tsarkova M.S., Philippov P.P., Sergeeva M.G., Senin I.I., Zernii E.Y., Zamyatnin A.A.Jr.
manifested in the tear fluid as a short-term increase in linoleic and alpha-linolenic acid-derived oxylipins

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