Screening of anti-inflammatory activity of 4.5- dihydroisoxazol-5-carboxamide (PAR-2 inhibitors) based on formaldehyde oedema model among white lab rats

Korsakov, M. K.; Fedorov, V. N.; Smirnov, N. A.; Shetnev, A. A.; Leonova, O. V.

Screening of anti-inflammatory activity of 4.5- dihydroisoxazol-5-carboxamide (PAR-2 inhibitors) based on formaldehyde oedema model among white lab rats

Korsakov, M. K., Fedorov, V. N., Smirnov, N. A., Shetnev, A. A., Leonova, O. V.

Дата публикации: 2023

Дата публикации в реестре: 2025-02-11T11:20:57Z

Аннотация:

Rheumatoid arthritis (RА) is an immune-inflammatory disease intrinsic to up to 1.0% of the world’s population. Standard drugs for RA therapy are basic medications, glucocorticoids and non-steroid anti-inflammatory drugs, which often only ease or hinder the course of disease, not curing the patient completely

Ключевые слова:
medicine, pharmacology, 4.5-dihydroisoxazol-5-carboxamide derivatives, formaldehyde oedema, PAR-2 inhibitors, rheumatoid arthritis

Тип: Article