Single HA2 mutation increases the infectivity and immunogenicity of a live attenuated H5N1 intranasal influenza vaccine candidate lacking NS1 - «Национальный агрегатор открытых репозиториев российских университетов» (НОРА)

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Single HA2 mutation increases the infectivity and immunogenicity of a live attenuated H5N1 intranasal influenza vaccine candidate lacking NS1

Дата публикации: 2021-04-27

Дата публикации в реестре: 2021-10-05T18:23:36Z

Аннотация:

Ключевые слова:
influenza vaccine, Influenza virus hemagglutinin, immunoglobulin A, immunoglobulin G, influenza vaccine, live vaccine, acidity, animal experiment, antibody response, article, controlled study, drug efficacy, epithelium cell, gene, hemagglutination, high temperature, human, human cell, immunization, immunogenicity, immunohistochemistry, influenza A (H5N1), mutation, nonhuman, nose mucosa, NS1 gene, pH, phenotype, virus resistance, virus titration, animal, blood, Cercopithecus, enzyme linked immunosorbent assay, female, genetics, immunology, Influenza virus A H5N1, intranasal drug administration, mouse, orthomyxovirus infection, pathogenicity, Vero cell, Avian influenza virus, human influenza virus, Mammalia, Mus, Orthomyxoviridae, Administration, Intranasal, Animals, Cercopithecus aethiops, Enzyme-Linked Immunosorbent Assay, Female, Humans, Immunoglobulin A, Immunoglobulin G, Influenza A Virus, H5N1 Subtype, Influenza Vaccines, Mice, Mutation, Orthomyxoviridae Infections, Vaccines, Attenuated, Vero Cells

Тип: info:eu-repo/semantics/journal-article

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