Novel oral anti-influenza prodrug candidate AV5075S - «Национальный агрегатор открытых репозиториев российских университетов» (НОРА)

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Novel oral anti-influenza prodrug candidate AV5075S

Ivachtchenko A.V.

Дата публикации: 2021-04-27

Дата публикации в реестре: 2021-10-05T18:23:58Z

Аннотация:

Ключевые слова:
4 acetamido 5 amino 3 (1 ethylpropoxy) 1 cyclohexene 1 carboxylic acid, 4 amino 5 (2,2 difluoroacetamido) 3 (1 ethylpropoxy)cyclohex 1 enecarboxylic acid, antivirus agent, av 5027, av 5075s, av 5092, av 5095, av 5095s, av 5102, av5092, av5095, av5095s, laninamivir, mesylic acid derivative, oseltamivir, prodrug, sialidase, unclassified drug, zanamivir, [ 4 (2,2 difluoroacetylamino) 5 amino 3 (1 ethyl propoxy) cyclohex 1 enercarboxylic acid, [ 5 amino 4 (2,2 difluoroacetylamino) 3 (1 ethyl propoxy) cyclohex 1 enecarboxylic acid] ethyl ester mesylate, antivirus agent, prodrug, animal experiment, animal model, antiviral activity, article, beagle, controlled study, drug bioavailability, drug blood level, drug efficacy, drug metabolism, drug potency, drug stability, drug synthesis, female, human, IC 50, in vitro study, in vivo study, influenza, influenza A (H3N2), Influenza virus, male, molecular docking, mouse, nonhuman, pneumonia, quantitative structure activity relation, rat, single drug dose, therapy effect, virus infection, animal, disease model, dog, intravenous drug administration, oral drug administration, Orthomyxoviridae Infections, Pneumonia, Viral, Sprague Dawley rat, treatment outcome, virology, Administration, Intravenous, Administration, Oral, Animals, Antiviral Agents, Disease Models, Animal, Dogs, Female, Male, Mice, Orthomyxoviridae Infections, Pneumonia, Viral, Prodrugs, Rats, Sprague-Dawley, Treatment Outcome

Тип: info:eu-repo/semantics/journal-article

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