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Repurposing Pan-HDAC Inhibitors for ARID1A-Mutated Ovarian Cancer
), diseases that have no effective therapy. Here, we show that ARID1A mutation confers sensitivity to pan-HDAC

Diaryl Pyrazoline, 1,3,4-Oxadizole, and 1,2,4-Triazole Pharmacophore Hybridization: Design, Synthesis, HDAC Inhibition, and Caspase 3/7 Activation Studies characterized. The compounds were tested for HDAC inhibitory properties on HDAC4 and HDAC8 isoforms, with a

Selective inhibitor of histone deacetylase 6 (tubastatin A) suppresses proliferation of hepatitis C virus replicon in culture of human hepatocytes of selective inhibitors of histone deacetylases HDAC6 and SIRT-2 - tubastatin A and 2-(3-phenethoxyphenylamino

Immunohistochemical Analysis of Epigenetic Markers in Cervical Pathologies Associated with Human Papillomavirus Infection. Immunohistochemical features analyzed included histone deacetylases (HDAC1, HDAC2) and DNA methyltransferases (DNMT1

Selective inhibitor of histone deacetylase 6 (tubastatin A) suppresses proliferation of hepatitis C virus replicon in culture of human hepatocytes of selective inhibitors of histone deacetylases HDAC6 and SIRT-2 - tubastatin A and 2-(3-phenethoxyphenylamino

Immunohistochemical Analysis of Epigenetic Markers in Cervical Pathologies Associated with Human Papillomavirus Infection. Immunohistochemical features analyzed included histone deacetylases (HDAC1, HDAC2) and DNA methyltransferases (DNMT1

Nortriptyline overcomes corticosteroid resistance in NK and NKT-like cells from peripheral blood of patients with chronic obstructive pulmonary diseaseHDAC2

Treatment of cardiovascular pathology with epigenetically active agents: Focus on natural and synthetic inhibitors of DNA methylation and histone deacetylation such as DNA methyltransferases (DNMTs), histone acetyltransferases, histone deacetylases (HDACs), etc. may

Epigenetic effects of enzastaurin – a new aspect in the mechanism of action of an anticancer drug from protein kinase inhibitors; 3) activity of HAT and HDAC1 enzymes; 4) expression levels of the genes encoding epigenetic

Epigenetic effects of enzastaurin - a new aspect in the mechanism of action of an anticancer drug from protein kinase inhibitors; 3) activity of HAT and HDAC1 enzymes; 4) expression levels of the genes encoding epigenetic

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