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Integrative analysis of miRNA and mRNA sequencing data reveals potential regulatory mechanisms of ACE2 and TMPRSS2. In this work we searched for putative ACE2 and TMPRSS2 expression regulation networks mediated by various miRNA

Alu RNA regulates the cellular pool of active ribosomes by targeted delivery of SRP9/14 to 40S subunits direct binding of SRP9/14 to 40S ribosomal subunits and requires Alu RNA as an assembly factor but its

Discovery of an essential nucleotidylating activity associated with a newly delineated conserved domain in the RNA polymerase-containing protein of all nidoviruses capping and protein-primed RNA synthesis, possibilities that remain to be explored in future studies

One severe acute respiratory syndrome coronavirus protein complex integrates processive RNA polymerase and exonuclease activities-synthesizing machinery to replicate the largest known RNA genomes. This protein complex is a fascinating example

Differences in structure and hibernation mechanism highlight diversification of the microsporidian ribosome-shaped conformation to bridge the mRNA decoding site and the large subunit tRNA binding sites, providing a reversible

Septin dynamics are essential for exocytosis attachment protein (SNAP), the adaptor protein that mediates NSF binding to the SNARE complex, did

Emergency services of viral RNAs: Repair and remodeling robustness or mutational tolerance, which is largely due to the functional degeneracy of many protein and RNA

Potential role of cellular miRNAs in coronavirus-host interplay interact with various viruses through several possible mechanisms including direct binding of viral RNA

Intrinsically disordered proteins of viruses: Involvement in the mechanism of cell regulation and pathogenesisIntrinsically disordered proteins (IDPs) possess the property of inherent flexibility and can

Structural basis for the regulatory function of a complex zinc-binding domain in a replicative arterivirus helicase resembling a nonsense-mediated mRNA decay helicaseAll positive-stranded RNA viruses with genomes > ∼7 kb encode helicases, which generally are poorly

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