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Rapid high-yield expression of a candidate influenza vaccine based on the ectodomain of M2 protein linked to flagellin in plants using viral vectorsBackground: The extracellular domain of matrix protein 2 (M2e) of influenza A virus is a promising
Protection against multiple influenza a virus strains induced by candidate recombinant vaccine based on heterologous m2e peptides linked to flagellinMatrix 2 protein ectodomain (M2e) is considered a promising candidate for a broadly protective
Construction and immunogenicity of a novel multivalent vaccine prototype based on conserved influenza virus antigens investigation, with long alpha-helix (LAH) from hemagglutinin stalk and ectodomain of matrix protein 2 ion
Flagellin-fused protein targeting M2e and HA2 induces potent humoral and T-cell responses and protects mice against various influenza viruses a subtypes current trend in the design of universal flu vaccines is the construction of recombinant proteins based
Cross-protective properties of an influenza vaccine based on HBc4M2e recombinant protein undergoing clinical trials. We created Uniflu candidate vaccine based on recombinant HBc4M2e protein
Prime-boost vaccination with a combination of proteosome-degradable and wild-type forms of two influenza proteins leads to augmented CTL response, we hypothesized that a recombinant vaccine utilizing a combination of proteosome
Combination of M2e peptide with stalk HA epitopes of influenza A virus enhances protective properties of recombinant vaccine intranasally with recombinant proteins comprising either one viral protein (the ectodomain of the M2 protein
Combined immunization with attenuated live influenza vaccine and chimeric pneumococcal recombinant protein improves the outcome of virus-bacterial infection in mice. The effect of combined immunization with live influenza vaccine and recombinant chimeric pneumococcal protein
M2e-based universal influenza vaccines: A historical overview and new approaches to development. The extracellular domain of the M2 protein (M2e) of influenza A virus is a conservative region, and an attractive
Vaccination potential of B and T epitope-enriched NP and M2 against Influenza A viruses from different clades and hosts viral proteins–nucleoprotein (NP) and matrix protein 2 (M2)—by B and T-cell epitopes not only human
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