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Intrinsically disordered proteins of viruses: Involvement in the mechanism of cell regulation and pathogenesisIntrinsically disordered proteins (IDPs) possess the property of inherent flexibility and can
Prediction of protein-protein interaction with cosine matricesThe protein-protein interaction prediction problemis one of the unsolved fundamental problems
Protein intrinsic disorder toolbox for comparative analysis of viral proteins-associated. High abundance of intrinsic disorder in envelope and matrix proteins from HIV-related viruses likely
Mass spectrometric approaches to study enveloped viruses: New possibilities for structural biology and prophylactic medicine macromolecules. Some examples of protein identification, virion proteomics, testing vaccine preparations
Prime-boost vaccination with a combination of proteosome-degradable and wild-type forms of two influenza proteins leads to augmented CTL response-cell cross-presentation by APCs, a mechanism that requires high levels of the antigenic protein. Therefore
Rapid high-yield expression of a candidate influenza vaccine based on the ectodomain of M2 protein linked to flagellin in plants using viral vectorsBackground: The extracellular domain of matrix protein 2 (M2e) of influenza A virus is a promising
Flagellin-fused protein targeting M2e and HA2 induces potent humoral and T-cell responses and protects mice against various influenza viruses a subtypes current trend in the design of universal flu vaccines is the construction of recombinant proteins based
M2e-based universal influenza vaccines: A historical overview and new approaches to development. The extracellular domain of the M2 protein (M2e) of influenza A virus is a conservative region, and an attractive
Gene editing by extracellular vesicles, and ability to cross biological barriers. Available molecular tools that enable loading of desired protein and
Influenza a virus proteins NS1 and hemagglutinin along with M2 are involved in stimulation of autophagy in infected cellsThe NS1 protein of influenza A virus is known to downregulate apoptosis early in infection in order
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