Synthesis of 4,6-disubstituted bicyclo[3.3.1]nona-3,6-dien-2-onesBicyclo[
3.3.1]nonane is
a fundamental structural unit in
a variety of biologically active natural
[3+2] Cycloaddition of o-nitrophenyl azide to 3a,6-epoxyisoindoles in substituted
3a,
6-epoxyisoindoles was performed. The 1,
3-dipolar addition reaction proceeded stereoselectively
Continuous-flow catalytic hydrogenation of 3a,6-epoxyisoindoles fragment of substituted fused 1-oxo-
3a,
6-epoxyisoindoles is described.
A continuous-flow hydrogenation
Crystal structure and Hirshfeld surface analysis of dimethyl (1R∗,3aS∗,3a1R∗,6aS∗,9R∗,9aS∗)-3a1,5,6,9a-tetrahydro-1H,4H,9H-1,3a:6a,9-diepoxyphenalene-2,3-dicarboxylateThe title diepoxyphenalene derivative, C 17 H 18 O
6 , comprises
a fused cyclic system containing