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Defects in the interferon system associated with a deficiency of natural killers and T-cells in patients with COVID-19 established: blockade of the production of IFN-α and IFN-γ against the background of a significant increase

Controversial role of neutrophilic granulocytes in the immunopathogenesis of COVID-19: correlation with imbalance of pro-inflammatory neutrophil-associated cytokines and interferon alpha deficiency. Objective. To specify the mechanisms of immunopathogenesis of COVID-19 based on a comparative immunological

High levels of cytokines IL-17A, IL-18, VEGF-A are biomarkers of the incompleteness of the immune inflammatory process, signaling the danger of developing postcovid syndrome in the period of COVID-19 reconvalescence, IL-8, IL-10, IL-17A, IL-18, VEGF-A and interferons IFN-α, IFN-γ. Patients and methods. IL-1b-4

THE ROLE OF NEUTROPHIL EXTRACELLULAR TRAPS (NETs) IN THE IMMUNOPATHOGENESIS OF SEVERE COVID-19: POTENTIAL IMMUNOTHERAPEUTIC STRATEGIES REGULATING NET FORMATION AND ACTIVITY; [РОЛЬ НЕЙТРОФИЛЬНЫХ ЭКСТРАЦЕЛЛЮЛЯРНЫХ СЕТЕЙ (NETs) В ИММУНОПАТОГЕНЕЗЕ ТЯЖЕЛОГО COVID-19: ПОТЕНЦИАЛЬНЫЕ ИММУНОТЕРАПЕВТИЧЕСКИЕ СТРАТЕГИИ, РЕГУЛИРУЮЩИЕ ПРОЦЕСС ФОРМИРОВАНИЯ И АКТИВНОСТЬ NETs] extracellular networks (NETs). In this review, we analyzed a large body of scientific literature devoted

Effects of recombinant IFN-α2b on the phenotype of neutrophil granulocyte subpopulations in patients with COVID-19 the innate immune response against SARS-CoV-2. Objective. To assess the effects of recombinant IFN-α2b

POSITIVE EFFECTS OF RECOMBINANT INTERFERON α2b ON THE PHENOTYPE OF CD16+IFNα/βR1-CD119+, CD16+IFNα/βR1+CD119- NEUTROPHIL GRANULOCYTE SUBSET IN PATIENTS WITH POST-COVID SYNDROME AND HERPESVIRUS INFECTIONSPost-COVID syndrome (PCS) is a multisystem inflammatory condition with manifestations of chronic

QUANTITATIVE AND PHENOTYPIC TRANSFORMATION OF CD16+IFNα/βR1 CD119+, CD16+IFNα/βR1+CD119-AND CD16+IFNα/βR1+CD119+ NEUTROPHIL GRANULOCYTES SUBSETS IN PATIENTS WITH POST-COVID SYNDROME the tonsils and the posterior wall of the pharynx. To determine the severity of the clinical PCS symptoms, a

Defects of immune system function in immunocompromised children with congenital cleft lip and palate and recurrent respiratory infections [Дефекты функционирования иммунной системы при рецидивирующих респираторных инфекциях у иммунокомпрометированных детей с врожденной расщелиной губы и нёба] of oral cavity. All patients were at the stage of preparation for surgery to correct a soft palate defect

Recombinant live attenuated influenza vaccine viruses carrying conserved T-cell epitopes of human adenoviruses induce functional cytotoxic T-cell responses and protect mice against both infections the development of an effective vaccine very challenging. In the current study, we designed a cross-reactive AdV

Notes on Study of Age and Growth of the Hyrcanian Frog, Rana pseudodalmatina, Eiselt et Schmidtler, 1971 in the Talysh MountainsThe article presents the first results of a study of age and growth of the Hyrcanian frog, Rana

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