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GRINDING ACTIVATION AS A WAY TO CHANGE THE BIOLOGICAL ACTIVITY AND PHYSICAL-CHEMICAL PROPERTIES OF DRUGS USING NICOTINAMIDE AS AN EXAMPLE
Uspenskaya E.V., Revtova A.Y., Kazymova I.V., Koldina A.M., Pleteneva T.V., Syroeshkin A.V., Pham M.H.
(microscopy, laser diffraction), infrared spectroscopy, biotesting using the method Spirotox, p
THE DEVELOPMENT OF METHOD FOR ACTIVATING PHARMACEUTICAL SUBSTANCES WITH SUBSEQUENT IN SITU STUDY OF MODIFIED POWDER PROPERTIES
Uspenskaya E., Kuzmina E.S., Quynh H.T.N., Timofeev A.A., Maximova T.V.
of the chiral center was revealed. The Spirotox method showed a 1.6-fold (P≤0.05) increase in biological
The effect of the deuterium depleted water on the biological activity of the eukaryotic cells
Syroeshkin A.V., Antipova N.V., Zlatska A.V., Zlatskiy I.A., Skylska M.D., Grebennikova T.V., Goncharuk V.V.
Monolayer scratch method
ARRHENIUS KINETICS IN THE EVALUATION OF THE BIOLOGICAL ACTIVITY OF PHARMACEUTICAL TINCTURES
Galkina D.A., Fatkulina O.A., Ogotoeva D.D., Levitskaya O.V., Uspenskaya E.V., Pleteneva T.V., Syroeshkin A.V.
Objective: To develop a method for identifying tinctures by assessing their biological activity
The effect of thermal sterilization and excipients on the stability of ascorbic acid in aqueous solutions
Syroeshkin A.V., Pleteneva T.V., Uspenskaya E.V., Levitskaya O.V., Barsegyun S.S., Zlatsky I.A., Tribot-Laspiere M.A.
) and its reactions with excipients for the improvement of the injection forms technology. Methods
Mechanical Transformation of Compounds Leading to Physical, Chemical, and Biological Changes in Pharmaceutical Substances
Syroeshkin A.V., Uspenskaya E.V., Pleteneva T.V., Morozova M.A., Zlatskiy I.A., Koldina A.M., Nikiforova M.V.
of the compounds was determined by the method of Spirotox. The activation energy was determined by Arrhenius
Preparation, characterization and studies of physicochemical and biological properties of drugs coating lactose in fluidized beds
Uspenskaya E.V., Pleteneva T.V., Syroeshkin A.V., Tarabrina I.V.
Sizer Nano ZS instrument in the nanoscale; Spirotox method for research of biological activity
New Approaches to Determining the D/H Ratio in Aqueous Media Based on Diffuse Laser Light Scattering for Promising Application in Deuterium-Depleted Water Analysis in Antitumor Therapy
Syroeshkin A.V., Uspenskaya E.V., Levitskaya O.V., Kuzmina E.S., Kazimova I.V., Quynh H.T.N., Pleteneva T.V.
nuclei in water and aqueous solutions were established. Using the Spirotox method, a «safe zone
ЭФФЕКТ СНИЖЕНИЯ ТОКСИЧНОСТИ ФТОРХИНОЛОНОВ В СРЕДАХ РАСТВОРЕНИЯ РАЗНОЙ ПРИРОДЫ
Казымова И.В., Татаринова А.Л., Успенская Е.В.
of fluoroquinlone (FTQ) drugs. For this the Spirotox original method was used in combination with the model scheme
Influence of Mechanical Loading on the Process of Tribochemical Action on Physicochemical and Biopharmaceutical Properties of Substances, Using Lacosamide as an Example: From Micronisation to Mechanical Activation
Uspenskaya E.V., Kuzmina E., Quynh H.T.N., Komkova M.A., Kazimova I.V., Timofeev A.A.
-IR and biopharmaceutical approaches. The SLS method demonstrated the spontaneous tendency toward surface-energy reduction

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